Does used to breed show quality goats are normally very large, as show goats are expected to be of large stature. For commercial meat production medium size does are normally preferred as they produce the same number of kids, but require less feed to do so.

As a general rule the more kids born per doe, the greater profit margins for the owner. Boer goats are polyestrous (they can breed throughout the year), they can reach sexual maturity at 5 months of age. A typical breeding program is to produce 3 kid crops every 2 years; meaning the does are pregnant for 5 months, nurse their kids for 3 months, and then are rebred. Multiple births are common and a 200% kid crop is achievable in managed herds. Usually first time does will have one kid, but it is possible for them to have more. After that, they will have an average of two kids each time.

Weaning size is largely controlled by how much milk the mother produces, along with how long she allows each kid to nurse. Does weaning large kids should be kept, those weaning small to medium kids should be removed from the herd.
The presence of a buck causes Does to come into oestrus (heat), which lasts about 24–72 hours. The gestation period for does varies from 149 to 155 days.

Boer Does are normally very good mothers, requiring only minimal attention from the owner; however, this is not always true when a Doe delivers her very first kid. First time Does should be supervised, as the mothering instinct may not manifest itself the first time she delivers. After the first kidding, Boer Does normally make excellent mothers. If after that a Doe does not present herself to have “mothering instincts”, it is best not to keep her.